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Trend Micro RootkitBuster was developed to be a rootkit scanner that offers ability to scan for hidden files, registry entries, processes, drivers and hooked system services, and MBR. It also includes the cleaning capability for hidden files and registry entries.

Master Boot Record (MBR) rootkit detection, gives RootkitBuster the ability to detect hidden MBR content. It can spot all variants of MBR rootkit in the wild. MBR rootkits first began appearing in the wild late 2007. New variants continue to appear.